Efficient Estimation of Realized Kinship from Single Nucleotide Polymorphism Genotypes
نویسندگان
چکیده
منابع مشابه
Efficiency of single-nucleotide polymorphism haplotype estimation from pooled DNA.
The efficiency of single-nucleotide polymorphism haplotype analysis may be increased by DNA pooling, which can dramatically reduce the number of genotyping assays. We develop a method for obtaining maximum likelihood estimates of haplotype frequencies for different pool sizes, assess the accuracy of these estimates, and show that pooling DNA samples is efficient in estimating haplotype frequenc...
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ژورنال
عنوان ژورنال: Genetics
سال: 2017
ISSN: 1943-2631
DOI: 10.1534/genetics.116.197004